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  4. Gibco™ Human BMP-7 Recombinant Protein

Gibco™ Human BMP-7 Recombinant Protein

Product Code. 11350852
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Quantity:
1 mg
10 μg
100 μg
Unit Size:
Each
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Product Code. 11350852

Brand: Gibco™ PHC9543

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Description

Recombinant Protein

Carrier-Free Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in sterile water containing 0.1% human serum albumin. Apportion the reconstituted protein into working aliquots and store at = -20°C. Make any further dilutions of the reconstituted protein in low endotoxin medium or a buffered solution containing a carrier protein such as heat inactivated FCS or tissue culture grade BSA. Storage: Store the lyophilized protein at = -20°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at = -20°C. Avoid repeated freeze-thaw cycles.

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P18075, P23359
For Use With (Application) Bioactivity
Formulation 10mM acetic acid with no preservative
Gene ID (Entrez) 12162, 655
Molecular Weight (g/mol) 38 kDa
Name Human BMP-7
Purification Method Purified
Quantity 1 mg
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <0.5 EU/μg
Gene Alias BMP; BMP7; BMP-7; bone moorphogenic protein-7; Bone morphogenetic protein; bone morphogenetic protein 7; bone morphogenetic protein 7 (osteogenic protein 1); bone morphogenetic protein 7 preproprotein; bone morphogenic protein 7; Eptotermin alfa; OP1; OP-1; Osteogenic protein 1; RP11-560A15.5
Common Name BMP-7
Gene Symbol Bmp7
Biological Activity ED50 = 8.31 ng/mL; determined by the dose-dependent induction of alkaline phosphatase production in ATDC-5 cells.
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Content And Storage -20°C
Classification Carrier-Free
Activity ED50 = 8.31 ng/mL; determined by the dose-dependent induction of alkaline phosphatase production in ATDC-5 cells.
Bioassay Induction of alkaline phosphatase in ATDC5 cells
Endotoxin Level <0.5 EU/μg
Shipping Condition Dry Ice
Expression System HEK293 cells
Protein Family Growth Factors & Receptors
Protein Form Recombinant, Ligand
Form Lyophilized
Protein Subtype BMPs (Bone Morphogenetic Proteins) & Related Factors
Research Category Bone Research, Stem Cell Research, Differentiation
Product Line Gibco
Purity or Quality Grade >95% by SDS-PAGE
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