Invitrogen™ Human Amyloid Precursor Protein Synthetic Peptide

Description

APP Synthetic Peptide, PEP-0048, from Invitrogen.

Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa. This peptide corresponds to 15 amino acids near the carboxy terminus of human APP.PEP-0048 can be used as a blocking peptide with polyclonal antibody PA5-19923.