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Proteintech™ Human ABCD1 ELISA Kit

Solid phase sandwich ELISA used to detect and quantify protein levels of endogenous ABCD1

Brand:  Proteintech™ KE00030-96T


Product Code. 16841456

  • € 269.00 / 96 tests

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Description

Description

  • Recognizes human ABCD1
  • ABCD1 known as adrenoleukodystrophy protein (ALDP)
    • Member of multi-pass membrane protein
    • Localized at peroxisome membrane
    • Mutations of ABCD1 cause X-ALD, an inherited neurodegenerative disease affecting the nervous system, white matter and adrenal cortex
      • Results in mental deterioration, corticospinal tract dysfunction and cortical blindness

Process:

  • Antibody specific for ABCD1 pre-coated onto microwells
  • ABCD1 protein in samples captured by the coated antibody after incubation
  • After extensive washing, another antibody specific ABCD1 is added to detect captured ABCD1 protein
  • For signal development, horseradish peroxidase (HRP)-conjugated antibody is added, followed by Tetramethyl-benzidine (TMB) reagent
  • Solution containing sulfuric acid used to stop color development and color intensity
    • Proportional to quantity of bound protein, measurable at 450 nm with correction wavelength set at 630 nm
Specifications

Specifications

NP_000024
6 pg/mL
Sandwich ELISA, Double Antibody
Plasma, Serum
Human
Human
<10%
Blue ice
3.5 hr.
31.25 to 2000 pg/mL
ISO 13485
Coated ELISA Kit
DAB
215
Solid
<10%
-20°C to +4°C
P33897
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