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Epredia™ Lab Vision™ Granzyme B Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ Granzyme B Ab-1, Mouse Monoclonal Antibody.

€ 127.50 - € 677.00

Especificaciones

Antigen Granzyme B Ab-1
Clone GZB01
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Productos 5
Código de producto Marca Form Quantity Precio Cantidad y disponibilidad  
Código de producto Marca Form Quantity Precio Cantidad y disponibilidad  
12649136
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Epredia™
MS-1157-S0
Concentrated 100 μL This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
N/A
12659136
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Epredia™
MS-1157-S1
Concentrated 500 μL
€ 451.00
500µL
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12639136
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Epredia™
MS-1157-S
Concentrated 1 mL
€ 677.00
1mL
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12629136
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Epredia™
MS-1157-R7
Prediluted 7 mL This item is currently unavailable or has been discontinued.
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N/A
12619136
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Epredia™
MS-1157-RQ
Ready-to-Use 12 mL This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
N/A
Descripción

Descripción

Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified. One of these, human granzyme B, is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. Exocytosis of granzyme-containing granules in the cytoplasm of the target cell leads to the induction of DNA fragmentation and apoptosis.

Host Species: Mouse

Clone: GZB01

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: N-terminal

Immunogen: Recombinant protein encoding the N-terminus of the mature granzyme B

Molecular Weight: 32 kDa

Positive Control: Hodgkin's lymphoma, Tonsil

Cellular Localization: Granular cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)

Especificaciones

Especificaciones

Granzyme B Ab-1
Immunohistochemistry (Paraffin)
Unconjugated
IVD
Recombinant protein encoding the N-terminus of the mature granzyme B
GZB01
Monoclonal
Mouse
Apoptosis
Primary
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