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Thermo Scientific™ GeneBLAzer™ H1-NFAT-bla HEK 293T Cells
GeneBLAzer™ H1-NFAT-bla HEK293T cells contain the human Histamine Receptor 1 (H1) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.
Brand: Thermo Scientific™ K1703
Description
GeneBLAzer™ H1-NFAT-bla HEK293T cells contain the human Histamine Receptor 1 (H1) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line. CellSensor™ NFAT-bla HEK293T cells (Cat. No. K1538) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.
The GeneBLAzer™ H1-NFAT-bla HEK293T cells are functionally validated for Z' and EC50 concentrations Histamine. In addition, GeneBLAzer™ H1-NFAT-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The H1 receptor is located in human bronchi, bronchioles, and bronchial muscle, smooth muscle of the ileum, and the uterus. H1 receptors play a role in various disorders, including allergic reactions and mood disorders.
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Specifications
NM_000861.3 | |
Dividing Cells | |
Fluorescence | |
H1 | |
Single Cell Clone Origin | |
2 x 106 Cells | |
HRH1, H1 | |
293T (HEK) | |
GPCR |
Cell-based beta lactamase reporter gene | |
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol. Includes: • GeneBLAzer™ H1-NFAT-bla HEK293T cells • GeneBLAzer™ H1-NFAT-bla HEK293T Assay Protocol • Certificate of Analysis The GeneBLAzer™ H1-NFAT-bla HEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
|
FRET | |
H1-NFAT-bla HEK293T cells, H1-NFAT-bla HEK293T Assay Protocol, Certificate of Analysis | |
GeneBLAzer™ | |
BLA (Beta-Lactamase) | |
Cell Line | |
GeneBLAzer™ |
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For Research Use Only. Not for use in diagnostic procedures.