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Thermo Scientific™ GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 Cells

Product Code. 10592754
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Quantity:
2 x 106 Cells
Unit Size:
Each
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Product Code. 10592754

Brand: Thermo Scientific™ K1708

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Description

GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells contain the human Dopamine Receptor 2 (D2) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells contain the human Dopamine Receptor 2 (D2) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line. GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cells (Cat. No. K1536) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Chimeric G protein, Gqo5.

The GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of apomorphine. In addition, GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The D2 receptor is found primarily in the brain. There are two forms of D2 which are created by alternate splicing: a short form and a long form. This assay uses the long form, although little difference in ligand binding or signaling has been seen between the two forms.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number NM_000795
Assay Entry Cell-based beta lactamase reporter gene
Cell State Dividing Cells
Content And Storage LiveBLAzer™-FRET B/G Loading Kit, Solution D, and other materials are required separately; please refer to the protocol.

Includes:
• GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells
• GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells should be stored in liquid nitrogen immediately upon receipt.
Description GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 Cells, 2 x 106 Cells, ∽2,000,000 cells/vial at 2,000,000 cells/mL Quantity of Cells, CHO-K1 Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage
Detection Method Fluorescence
For Use With (Application) FRET
Gene Symbol D2
Includes GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells, GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 Assay Protocol, Certificate of Analysis
Population Status Single Cell Clone Origin
Product Line GeneBLAzer
Quantity 2 x 106 Cells
Reporter Gene BLA (Beta-Lactamase)
Sample Type CHO-K1
Target Entry DRD2, D2
Type CHO-K1 Cells
Cell Line CHO-K1
System Type GeneBLAzer™
Druggable Target GPCR
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For Research Use Only. Not for use in diagnostic procedures.

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