missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Fumonisin B2, 96+%, Thermo Scientific Chemicals
Click to view available options
Quantity:
1 mg
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Fumonisin B2 is a fumonisin mycotoxin produced by the fungus Fusarium
• Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than B1 and can inhibit sphinganine-N-acetyltransferase (ceramide synthase)
Applications
• In vitro and in vivo studies have shown Fumonisin B2 can induce apoptosis
• It can inhibit de novo sphingolipid biosynthesis
• It is also considered an Aspergillus metabolite
• It shows cytotoxicity against a panel of seven rat hepatoma cell lines, and MDCK cell line
• It induces hepatocyte nodule formation, a marker of cancer initiation, in rats
Specifications
Specifications
CAS | 116355-84-1 |
Assay Percent Range | 96+% |
Molecular Formula | C34H59NO14·3H2O |
Quantity | 1 mg |
Synonym | fumonisin b2, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid |
Solubility Information | Solubility in water: .. Other solubilities: soluble in methanol |
InChI Key | UXDPXZQHTDAXOZ-FWPUDPCBSA-N |
SMILES | CCCCC(C)C(C(CC(C)CCCCCCC(CC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O |
IUPAC Name | (2S)-2-[2-[(5R,6R,7S,9S,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid |
Molecular Weight (g/mol) | 759.9 |
Show More |
Safety and Handling
Product Identifier
- Fumonisin B2
- Danger
- Acute toxicity Category 1
- Carcinogenicity Category 2
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
- H310-Fatal in contact with skin.
- H330-Fatal if inhaled.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H351-Suspected of causing cancer.
- H335-May cause respiratory irritation.
- H300-Fatal if swallowed.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P302+P352-IF ON SKIN: Wash with plenty of water/.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- P361-Take off immediately all contaminated clothing.
RUO – Research Use Only
missing translation for 'provideContentCorrection'
missing translation for 'productTitle'