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Fluorescein-ERM (LRRKtide)

Brand: Invitrogen PV4901

Product Code. 10258044

€ 926.00 / Each

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Description

A fluorescein-labeled peptide substrate based upon ezrin/radixin/moesin (ERM) that is phosphorylated by LRRK2 and LRRK2 mutants.

For use in combination with the LanthaScreen™ Tb-anti-ERM (pLRRKtide) Antibody (PV4899) to evalute inhibitors in medium to high throughput screening applications.

Specifications

Amino Acid Sequence	Fluorescein-GAGRLGRDKYKTLRQIRQ
Content And Storage	400 μM Fluorescein-ERM (LRRKtide) peptide substrate in water. Store at -20°C and protect from light.
Quantity	1 mg
Substrate Properties	Peptide-Based Substrate
Target Enzyme	Serine/Threonine Kinases
Label or Dye	FITC (Fluorescein)
Shipping Condition	Dry Ice
Validated Kinases	LRRK2

Assay Entry	Biochemical terbium phospho-specific activity
Detection Method	Fluorescence
Substrate	ERM (LRRKtide)
Substrate Type	Kinase Substrate
Gene ID (Entrez)	120892
Molecular Weight (g/mol)	2475.8 Da
Target Entry	LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2

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Documents

Product Information

Manuals

LRRK2 R1441C LanthaScreen Binding Assay Validation Packet Version: v1.1 File size: 248.3 kB

LRRK2 R1441C LanthaScreen Terbium Activity Assay Validation Packet Version: v1.1 File size: 214.3 kB

LRRK2 I2020T LanthaScreen Binding Assay Validation Packet Version: v1.1 File size: 249.3 kB

LRRK2 I2020T LanthaScreen Terbium Activity Assay Validation Packet Version: v1.1 File size: 213.7 kB

Certificates

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Lot Number

5 results found

Lot Number	Certificate Type	Date	Catalog Number
Lot Number2682386B	Certificate TypeCertificate of Analysis	Date12/09/2023	Catalog NumberPV4901
Lot Number2682386A	Certificate TypeCertificate of Analysis	Date28/07/2023	Catalog NumberPV4901
Lot Number2422941C	Certificate TypeCertificate of Analysis	Date15/04/2023	Catalog NumberPV4901
Lot Number2422941B	Certificate TypeCertificate of Analysis	Date02/12/2022	Catalog NumberPV4901
Lot Number2422941A	Certificate TypeCertificate of Analysis	Date15/04/2022	Catalog NumberPV4901

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