missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Crosslinking, Labeling and Protein Modification
  5. Crosslinking Reagents
  6. Thermo Scientific™ EZ-Link™ Maleimide-PEG4-DBCO

Thermo Scientific™ EZ-Link™ Maleimide-PEG4-DBCO

Product Code. 17611586 Shop All Thermo Scientific Products
Click to view available options
Quantity:
25 mg
10 x 1 mg
Unit Size:
25mg
Pack of 10
This item is not returnable. View return policy

Product Code. 17611586

Brand: Thermo Scientific™ C20041

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

A sulfhydryl reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications. The thiol/sulfhdryl reactive maleimide can be used to label a variety of thiol containing moieties such as free cystines in proteins, peptides, or other (bio)molecules.

  • A sulfhydryl reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications
  • The thiol/sulfhdryl reactive maleimide can be used to label a variety of thiol containing moieties such as free cystines in proteins, peptides, or other (bio)molecules
  • Once a protein or (bio)molecule is DBCO labeled, it can undergo a copper-free azide-alkyne cycloaddition reaction to form a stable triazole linkage with an azide labeled coupling partner
  • Can be used to create diverse conjugates with the biorthogonal coupling between an alkyne and azide (supplied separately)
  • The coupling or crosslinking procedure is typically done in two steps:
    • First, a protein or thiol containing molecule is labeled with a DBCO group and excess crosslinker is removed
    • Second, an azide containing moiety (prepared independently) is introduced into the same system as the DBCO moiety
    • Labeling occurs under biological conditions without the introduction of any additional reagents such as a copper catalyst
  • Reagent readily dissolves in water-miscible solvents for dilution into aqueous reaction mixtures
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Azide-Sulfhydryl
Cleavable No
Description Maleimide-PEG4-DBCO
Molecular Weight (g/mol) 647.74
PEGylated Yes
Spacer Arm Length 29.7 Å
Content And Storage Upon receipt store desiccated at -20°C.
Cell Permeability Not determined
Shipping Condition Wet Ice
Product Line EZ-Link No-Weigh
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Maleimide, DBCO
Spacer Medium (10 to 30 Å)
Form Solid
Quantity 25 mg
Solubility DMF, DMSO
Format Standard, Single-use
Water Soluble No
Product Type Crosslinker
Show More Show Less
Correction du contenu d'un produit

Veuillez fournir vos retours sur le contenu du produit en remplissant le formulaire ci-dessous.

Nom du produit

En cliquant sur Soumettre, vous reconnaissez que vous pouvez être contacté par Fisher Scientific au sujet des informations que vous avez fournies dans ce formulaire. Nous ne partagerons pas vos informations à d'autres fins. Toutes les informations de contact fournies seront également conservées conformément à notre politique de confidentialité. Politique de confidentialité.

Merci de nous aider à améliorer notre site web. Votre commentaire a été soumis