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Dimethyl biphenyl-4,4'-dicarboxylate, 98%, Thermo Scientific™
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Quantity:
1 g
5 g
25 g
Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
Applications
Dimethyl biphenyl-4,4′-dicarboxylate is used as a hepatoprotectant in the treatment of chronic hepatitis. At 250 µg/ml, it has been shown to stimulate JAK/STAT signaling and to induce the expression of interferon-α stimulated genes in a HepG2 cell line. It has been used to study hepatic fibrosis and chronic hepatocellular damage. It appears to normalize alanine aminotransferase (ALT) in cases where levels of ALT are elevated. It may be employed as starting reagent for the synthesis of dimethyl 2-fluoro-and 2,2′-difluorobiphenyl-4,4′-dicarboxylates.
Solubility
Insoluble in water.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Dimethyl biphenyl-4,4′-dicarboxylate is used as a hepatoprotectant in the treatment of chronic hepatitis. At 250 µg/ml, it has been shown to stimulate JAK/STAT signaling and to induce the expression of interferon-α stimulated genes in a HepG2 cell line. It has been used to study hepatic fibrosis and chronic hepatocellular damage. It appears to normalize alanine aminotransferase (ALT) in cases where levels of ALT are elevated. It may be employed as starting reagent for the synthesis of dimethyl 2-fluoro-and 2,2′-difluorobiphenyl-4,4′-dicarboxylates.
Solubility
Insoluble in water.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Specifications
Specifications
Melting Point | 212°C to 216°C |
Quantity | 1 g |
Beilstein | 2055852 |
Solubility Information | Insoluble in water. |
Formula Weight | 270.29 |
Percent Purity | 98% |
Chemical Name or Material | Dimethyl biphenyl-4,4'-dicarboxylate |
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Lot Number | Certificate Type | Date | Catalog Number |
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I6060A | Certificate of Analysis | 07/12/2021 |
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