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Decitabine, MedChemExpress
MedChemExpress Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.
Brand: Medchem Express HY-A0004
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Description
Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.Specifications
| Decitabine | |
| White | |
| C8H12N4O4 | |
| 5-Aza-2'-deoxycytidine 5-AZA-CdR NSC 127716 | |
| O=C1N=C(N)N=CN1[C@H](O[C@@H]2CO)C[C@@H]2O | |
| 228.21 | |
| Research | |
| Cancer-programmed cell death |
| 2353-33-5 | |
| Research | |
| 100 mg | |
| DMSO : ≥ 50 mg/mL (219.10 mM) ∣H2O : 20 mg/mL (87.64 mM; Need ultrasonic) | |
| 228.21 | |
| 95.0% | |
| Solid |
Research purposes only