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Decitabine, MedChemExpress

MedChemExpress Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.

Brand: Medchem Express HY-A0004

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Product Code. 16428258

POA / 10mg

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Description

Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.

Specifications

Chemical Name or Material	Decitabine
Color	White
Molecular Formula	C₈H₁₂N₄O₄
Synonym	5-Aza-2'-deoxycytidine 5-AZA-CdR NSC 127716
SMILES	O=C1N=C(N)N=CN1[C@H](O[C@@H]2CO)C[C@@H]2O
Formula Weight	228.21
Grade	Research
For Use With (Application)	Cancer-programmed cell death

CAS	2353-33-5
Purity Grade Notes	Research
Quantity	10 mg
Solubility Information	DMSO : ≥ 50 mg/mL (219.10 mM) ∣H2O : 20 mg/mL (87.64 mM; Need ultrasonic)
Molecular Weight (g/mol)	228.21
Percent Purity	95.0%
Physical Form	Solid

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Decitabine, MedChemExpress

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