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  8. 16487976

Decitabine, MedChemExpress

MedChemExpress Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.

Brand:  Medchem Express HY-A0004

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Product Code. 16487976

  • € 78.30 / 100mg

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Description

Description

Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.
Specifications

Specifications

Decitabine
White
C8H12N4O4
5-Aza-2'-deoxycytidine 5-AZA-CdR NSC 127716
O=C1N=C(N)N=CN1[C@H](O[C@@H]2CO)C[C@@H]2O
228.21
Research
Cancer-programmed cell death
2353-33-5
Research
100 mg
DMSO : ≥ 50 mg/mL (219.10 mM) ∣H2O : 20 mg/mL (87.64 mM; Need ultrasonic)
228.21
95.0%
Solid
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