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Thermo Fisher Scientific DDM/CHS Solution (10:1)
A ready-to-use solution for solubilization of membrane proteins while maintaining structural integrity and activity.
Brand: Thermo Fisher Scientific A50942
120.67 EUR valid until 2025-03-29
Use promo code "24111" to get your promotional price.
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”24111” to get your promotional price
Description
- A ready-to-use solution for solubilization of membrane proteins while maintaining structural integrity and activity
- The stable pre-formulated solution contains a mixture of dodecyl-β-D-maltoside (DDM) (100 mg/mL) and cholesteryl hemisuccinate (CHS) (10 mg/mL) in deionized water with final concentrations of 10% and 1%, respectively
- Typical working concentrations are 1% DDM/0.1% CHS for protein extraction and 0.1% DDM/0.01% CHS for protein purification
Features of DDM/CHS Solution include:
- Ready-to-use liquid formulation
- Mixture of nonionic detergent, DDM, with dual hydrophobic/hydrophilic properties and anionic detergent, CHS, that aids in the stabilization of large unilamellar vesicles
- DDM/CHS micelles aid in solubilization of membrane proteins while preserving structure and function
- Suitable for protein solubilization and stabilization for single particle cryo-EM analysis
Properties of DDM:
- Molecular formula: C24H46O11
- Molecular weight: 510.6 g/mol
- Detergent class: Non-ionic
- Micelle molecular weight: 50,000 g
- Critical micelle concentration (CMC): 0.17 mM (0.009% w/v) in water; 0.12 mM (0.006% w/v) in 0.2 M NaCl
Properties of CHS:
- Molecular formula: C31H50O4 · C4H11NO3
- Molecular weight: 607.9 g/mol
- Detergent: Ionizable anionic
- Function: Stabilizes large unilamellar vesicles
Specifications
| Liquid | |
| 10 x 1 mL |
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Certificates
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5 results found
| Lot Number | Certificate Type | Date | Catalog Number |
|---|---|---|---|
| ZH400524 | Certificate of Analysis | 15/10/2024 | A50942 |
| ZD389115 | Certificate of Analysis | 11/04/2024 | A50942 |
| YI379664 | Certificate of Analysis | 11/10/2023 | A50942 |
| YC368908 | Certificate of Analysis | 15/03/2023 | A50942 |
| YA365348 | Certificate of Analysis | 25/01/2023 | A50942 |
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Product Title
Thermo Fisher Scientific DDM/CHS Solution (10:1) > 10 x 1 mL
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