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Tocris Bioscience™ CY 09

Inflammasomes Inhibitors

€ 266.00 - € 963.00

Specifications

Chemical Name or Material 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid
CAS 1073612-91-5
Molecular Formula C19H12F3NO3S2
Purity 98%
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18783198
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Tocris Bioscience™
6436/10
10 mg
€ 266.00
10mg
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18791108
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Tocris Bioscience™
6436/50
50 mg
€ 963.00
50mg
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Description

Description

NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation. Displays therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes. Exhibits no activity for hERG (10 μM).
Specifications

Specifications

4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid
1073612-91-5
C19H12F3NO3S2
98%
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
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