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Gibco™ CTS™ Vitronectin (VTN-N) Recombinant Human Protein, truncated

Gibco™ CTS (Cell Therapy Systems) Vitronectin (VTN-N) Recombinant Human Protein provides a defined surface for feeder-free culture of human pluripotent stem cells (PSCs). When used with CTS Essential 8 Medium (A2656101), CTS Vitronectin has been proven to maintain pluripotency and normal growth characteristics in multiple PSC lines.

Brand:  Gibco™ CTS279S3

294.50 EUR valid until 2024-12-31
Use promo code "21952" to get your promotional price.


Product Code. 17606435

  • € 310.00 / 1mL

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Description

Description

  • Gibco CTS (Cell Therapy Systems) Vitronectin (VTN-N) Recombinant Human Protein provides a defined surface for feeder-free culture of human pluripotent stem cells (PSCs)
  • When used with CTS Essential 8 Medium (A2656101), CTS Vitronectin has been proven to maintain pluripotency and normal growth characteristics in multiple PSC lines
  • In addition, CTS Vitronectin has been shown to support PSC growth for >8 passages without any signs of karyotypic abnormalities and to maintain the ability of PSCs to differentiate into all three germ line lineages
  • The VTN-N variant of vitronectin supports human pluripotent stem cell attachment and survival better than wild-type vitronectin when used in conjunction with Essential 8 Medium

Additional Features of CTS Vitronectin include:

  • Designed for clinical research – USP Chapter 1043* and Ph Eur 5.2.12** considered in the design
  • Animal origin-free – for reduced variability and contamination risk in PSC cultures
  • Optimized – designed for use with CTS Essential 8 Medium
  • Consistent – supports seamless transition from RUO Vitronectin
  • Traceable – documentation includes COO and COA
  • Controlled – manufactured in compliance with ISO-13485

Designed for cell and gene therapy development and manufacturing

Both USP Chapter 1043 and Ph. Eur. 5.2.12 have been considered in the design of CTS Vitronectin, and this product is the only such product labeled with 'For Research Use or Manufacturing of Cell, Gene, or Tissue-Based Products. CAUTION: Not intended for direct administration to humans or animals.' Traceability documentation is provided with the product and includes a Certificate of Analysis (COA) and Certificate of Origin (COO) to support regulatory filings.

Animal origin–free system

CTS Vitronectin is animal origin–free to help reduce contamination risk and variability associated with animal-origin raw materials compared to human plasma–derived vitronectin and standard basement membrane extracts (BMEs).

Optimized and defined surface

Unlike standard BMEs, CTS Vitronectin is based on the N-variant design of vitronectin (VTN-N) from the laboratory of James Thomson for use with Essential 8 Medium and has been shown to support human pluripotent stem cell attachment and survival better than wild type vitronectin. CTS Vitronectin provides an optimal environment for feeder-free pluripotent stem cell culture.

Seamless transition from bench to clinic

PSC cultures expanded in other feeder or feeder-free systems can be transitioned to CTS Essential 8 Medium and CTS Vitronectin with minimal adaptation.

Manufacturing control and traceability

CTS Vitronectin is manufactured at a site that uses methods and controls that conform with cGMP for medical devices, 21 CFR Part 820. Our FDA-registered manufacturing sites are ISO 13485– and ISO 9001–certified. Full traceability documentation such as Certificate of Origin and Certificate of Analysis are available.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

0.81–0.99 mg/mL
Pluripotent Stem Cell Matrix
Sterile-filtered
Animal Origin-Free
E. coli
Cell and Gene Therapy Research, Development, and Manufacturing
Human
1 mL cryopreserved vial

Store at -70°C.
Dry Ice
ISO 13485
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For Research Use or Manufacturing of Cell, Gene, or Tissue-Based Products. CAUTION: Not intended for direct administration into humans or animals.