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Tocris Bioscience™ CRT 0066101

Potent protein kinase D (PKD) inhibitor

Brand:  Tocris Bioscience™ 4975/10

Product Code. 18727286

  • € 377.00 / 10mg

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Description

Description

CRT 0066101 is a potent inhibitor of protein kinase D (PKD); inhibits all PKD isoforms (IC50 values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively). Exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCα, MEK, ERK, c-Raf and c-Src. Reduces proliferation and cell viability of pancreatic cancer cells expressing moderate levels of endogenous PKD1/2. Orally bioavailable.
Specifications

Specifications

>98%
CRT 0066101
CRT 0066101
10 mg
411.33
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