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Tocris Bioscience™ CPI 203
BET bromodomain inhibitor; arrests cell cycle at G1 phase
Brand: Tocris Bioscience™ 5331/10
265.22 EUR valid until 2024-12-16
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This item is not returnable.
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Description
CPI 203 is a BET bromodomain inhibitor. Downregulates Myc expression, causes G1 cell cycle arrest and attenuates cell proliferation in human pancreatic neuroendocrine tumors. Arrests the growth of T cell acute lymphoblastic leukemia cells in vitro (EC50 = 91.2 nM). Also enhances the antitumor effect of rapamycin (Cat. No. 1292) in vitro and attenuates rapamycin induced Akt activation. Also enhances fibroblast reprogramming to hiPSCs at low concentration. Orally bioavailable.Specifications
| >98% | |
| CPI 203 | |
| CPI 203 |
| 10 mg | |
| 399.9 |
For Research Use Only