missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. General Cell Based Assays
  6. 10042863

Thermo Scientific™ CellSensor™ c-Fos-bla ME-180 Cell Line

The CellSensor™ c-fos-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the c-fos response element stably integrated into ME-180 cells.

Brand:  Thermo Scientific™ K1650

Product Code. 10042863

  • € 11620.00 / Each

Please to purchase this item. Need a web account? Register with us today!

Explore more special offers
This item is not returnable. View return policy

Description

Description

The CellSensor™ c-fos-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the c-fos response element stably integrated into ME-180 cells. To construct this cell line, the c-fos-bla construct was transduced into ME-180 cells by lentivirus. Flow cytometry was used to isolate cells responsive to epidermal growth factor (EGF). This cell line is validated for DMSO tolerance, cell number, stimulation time, substrate loading time, as well as Z' and EC50 concentrations for EGF. The CellSensor™ c-fos-bla ME-180 cell line is responsive to EGF, HGF, IL-6, OSM, TNFα, IL-1-alpha; and PMA/Thaps, and can be used to probe the JNK/P38/MAPK and JAK/STAT signaling pathways. This cell line can be adapted for high-throughput screening of agonist or antagonist compound libraries. Candidate drugs can also be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Cell-based beta lactamase reporter gene
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Fluorescent
beta-lactamase reporter gene under control of the c-Fos response element stably integrated into ME-180 cells
1 Vial
STAT1, STAT3, JAK1, EGFR, ERK1/2, p38, MAPK pathway, RAF, JAK2, c-MET, JNK, JAK/STAT (IFN gamma, IL-6/OSM) pathway, RON, MEK
CellSensor™
Dividing Cells
CellSensor™ c-Fos-bla ME-180 Cell Line, 1Vial, ∽ 2,000,000 cells/vial at 2,000,000 cells/mL Quantity of Cells, c-Fos-bla ME-180 Cell Line, Fluorescent Detection Method, CellSensor™ Druggable Target, Adherent Growth Properties, Liquid Nitrogen Storage
Pharma and biopharma, drug discovery and development, target and lead identification and validation, pathway biology, cellular pathway analysis assays, cellsensor™ cellular pathway assays
CellSensor™
c-Fos-bla ME-180
Cell Line
Signaling Pathway
Product Suggestions

Product Suggestions

Videos
SDS
Documents Certificates

Certificates

A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.

1 results found
Lot Number Certificate Type Date Catalog Number
Lot Number34537 Certificate TypeCertificate of Analysis Date15/04/2017 Catalog NumberK1650
Special Offers

Special Offers

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
Thermo Scientific™ CellSensor™ c-Fos-bla ME-180 Cell Line > 1 Vial

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.

For Research Use Only. Not for use in diagnostic procedures.