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CD31 Monoclonal Antibody (LCI-9), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA182381
380.80 EUR valid until 2025-03-16
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Description
Mouse anti Pig CD31 antibody, clone LCI-9 recognizes porcine Platelet endothelial cell adhesion molecule, also known as CD31 or PECAM-1.
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Specifications
| CD31 | |
| Monoclonal | |
| Conc. Not Determined | |
| tissue culture supernatant with 0.09% sodium azide | |
| Q95242 | |
| Pecam1 | |
| Porcine CD31/human IgGFc fusion protein. | |
| RUO | |
| 396941 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Flow Cytometry, Immunohistochemistry (Frozen) | |
| LCI-9 | |
| Unconjugated | |
| Pecam1 | |
| C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule | |
| Mouse | |
| 2 mL | |
| Primary | |
| Porcine | |
| Antibody | |
| IgM |
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Product Title
CD31 Monoclonal Antibody (LCI-9), Invitrogen™ > 2 mL; Unconjugated
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