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Thermo Scientific Chemicals Calpain Inhibitor I, 95+%

Product Code. 15454289
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Quantity:
5 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

 

It inhibits apoptosis in thymocytes and metamyelocytes. It also inhibits cell cycle progression at the G1/S border and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation. ALLN inhibits the proteolysis of IκBα and IκBβ by the ubiquitin-proteasome complex. ALLN also prevents nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Specifications

Quantity 5 mg
Description White
Content And Storage -30°C to -10°C
For Use With (Application) An inhibitor of both Calpain I and II
CAS 110044-82-1
Molecular Formula C20H37N3O4
Formula Weight 383.53
Synonym Ac-LLnL-CHO; ALLN
Form Powder
Beilstein 7656053
InChI Key FMYKJLXRRQTBOR-BZSNNMDCSA-N
SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C=O
IUPAC Name (2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-4-methyl-N-[(2S)-1-oxohexan-2-yl]pentanamide
Molecular Weight (g/mol) 383.53
Assay 95+%
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RUO – Research Use Only

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