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Tocris Bioscience™ AZ 10397767

Potent CXCR2 antagonist

Specifications

Product Type	Antagonist
Target Proteins	Chemokine Receptor
CAS	333742-63-5
Molecular Formula	C₁₅H₁₄ClFN₄O₂S₂
Formula Weight	400.88g/mol

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Products 2

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
18777686 View Documents missing translation for 'viewProductCertificates'	Tocris Bioscience™ 5872/10	10 mg	N/A	N/A

18797936 View Documents missing translation for 'viewProductCertificates'	Tocris Bioscience™ 5872/50	50 mg	N/A	N/A

Description

Potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable.

Specifications

Product Type	Antagonist
CAS	333742-63-5
Formula Weight	400.88g/mol
For Use With (Application)	Chemokine Receptor Antagonists

Target Proteins	Chemokine Receptor
Molecular Formula	C₁₅H₁₄ClFN₄O₂S₂
Content And Storage	Store at -20°C

For Research Use Only

Tocris Bioscience™ AZ 10397767

Specifications

Description

Specifications

Documents