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Ampicillin Trihydrate, MP Biomedicals™ Product Code.: 11484582
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Ampicillin Trihydrate, MP Biomedicals™

Product Code. 11484582 Shop All MP Biomedicals Products
25 g
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Quantity:
5 g
25 g
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Product Code. 11484582

Brand: MP Biomedicals 219014725

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Description

Active as a broad-spectrum antibiotic. Ampicillin Trihydrate, MP Biomedicals is a semi-synthetic derivative of penicillin that is commonly used to select for ampicillin resistance in mutated and transformed cells. It is also used for enhancing luminol che

Ampicillin trihydrate is a β-lactam antibiotic with an amino group side chain attached to the penicillin structure. It is a penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.

  • Inactivated by beta-lactamases; therefore, a beta-lactamase inhibitor should be considered when using ampicillin
  • Antimicrobial spectrum: gram-negative and gram-positive bacteria.
    • Against gram-positive bacteria, ampicillin has a similar mode of action as benzylpenicillin
    • Against gram-negative bacteria, it has a similar mode of action as chloramphenicol and tetracyclines
  • Bactericidal only to growing E. coli. Inhibits cell wall synthesis via cleavage of β-lactam ring of ampicillin by β-lactamase
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 7177-48-2
Molecular Formula C16H25N3O7S
Molecular Weight (g/mol) 403.45
InChI Key RXDALBZNGVATNY-CWLIKTDRSA-N
Synonym Aminobenzylpenicillin trihydrate, alpha-Aminobenzylpenicillin trihydrate ;D[-]-α-Aminobenzylpenicillin, 6-[D(-)-α-Aminophenylacetamido]penicillanic acidShow MoreShow Less
PubChem CID 23565
ChEBI CHEBI:31209
IUPAC Name (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;trihydrate
SMILES CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.O.O.O

Specifications

Physical Form Powder
Melting Point 198°C to 200°C (literature)
Concentration Working Concentration: 100mg/liter for both gram positive and gram negative bacteria. It is typically stable in media at 37°C for approximately 3 days.
Quantity 25 g
Solubility Information Soluble in 1M Ammonium Hydroxide (50mg/mL), dilute acids (50mg/mL 1M HCl) or bases; slightly soluble in water (10mg/mL); practically insoluble in alcohol, chloroform, ether and fixed oils.
Formula Weight 403.46

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Safety and Handling

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Product Identifier
  • Ampicillin Trihydrate
 Signal Word
  • Danger
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Respiratory sensitiser Category 1
  • Skin corrosion/irritation Category 2
  • Skin sensitiser Category 1
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H317-May cause an allergic skin reaction.
  • H319-Causes serious eye irritation.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P101-If medical advice is needed, have product container or label at hand.
  • P102-Keep out of reach of children.
  • P103-Read label before use.
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P284-¢In case of inadequate ventilation! wear respiratory protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321-Specific treatment (see on this label).
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : Ampicillin Trihydrate
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