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Amlodipine besylate, Tocris Bioscience™

Product Code. 18702684
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Quantity:
50 mg
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This item is not returnable. View return policy

Description

CaV1.x blocker

L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC50 = 25 μM).

Specifications

CAS 111470-99-6
Molecular Formula C26H31ClN2O8S
Quantity 50 mg
Synonym amlodipine besylate, amlodipine besilate, cardiorex, amlodipine benzenesulfonate, istin, amdepin, amdipin, amlodin, amlogard, amlopin
InChI Key ZPBWCRDSRKPIDG-UHFFFAOYSA-N
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O
IUPAC Name benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Molecular Weight (g/mol) 567.05
PubChem CID 60496
ChEBI CHEBI:2669
Formula Weight 567.05
Percent Purity 98%
Chemical Name or Material Amlodipine besylate
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