missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Isoquinolines and derivatives
  7. ACT 335827, Tocris Bioscience™

ACT 335827, Tocris Bioscience™

Product Code. 30002042
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective OX1 antagonist

Potent and selective orexin OX1 receptor antagonist (Kb values are 41 and 560 nM for OX1 and OX2 receptors respectively). Elicits anxiolytic effects in vivo. Brain penetrant and orally available.

Chemical Identifiers

CAS 1354039-86-3
Molecular Formula C31H38N2O5
Molecular Weight (g/mol) 518.654
InChI Key HXHOBPVRRPCTLG-SETSBSEESA-N
Synonym compound 9 pmid: 23589487, 2r-2-1s-1-3,4-dimethoxyphenyl methyl-6,7-dimethoxy-3,4-dihydro-1h-isoquinolin-2-yl-2-phenyl-n-propan-2-ylacetamide, ar,1s-1-3,4-dimethoxyphenyl methyl-3,4-dihydro-6,7-dimethoxy-n-1-methylethyl-a-phenyl-2 1h-isoquinolineacetamide, r-2-s-1-3,4-dimethoxybenzyl-6,7-dimethoxy-3,4-dihydroisoquinolin-2 1h-yl-n-isopropyl-2-phenylacetamide
PubChem CID 54765113
IUPAC Name (2R)-2-[(1S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-2-phenyl-N-propan-2-ylacetamide
SMILES CC(C)NC(=O)C(C1=CC=CC=C1)N2CCC3=CC(=C(C=C3C2CC4=CC(=C(C=C4)OC)OC)OC)OC

Specifications

Quantity 10 mg
Formula Weight 518.64
Chemical Name or Material ACT 335827
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.