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Tocris Bioscience™ AC 710
Potent and selective PDGFR family inhibitor
€ 356.00 - € 1400.00
Specifications
| Purity | >99% |
|---|---|
| Description | AC 710 |
| Molecular Weight (g/mol) | 562.7 |
| Product Type | AC 710 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18720278
|
Tocris Bioscience™
5013/10 |
10 mg |
€ 356.00
10mg |
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|
18796119
|
Tocris Bioscience™
5013/50 |
50 mg |
€ 1400.00
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Potent PDGFR family inhibitor (IC50 values are 1.2, 2, 7.7 and 10.5 nM for KIT, FLT3, PDGFRβ and CSF1R respectively; Kd = 1.3 nM for PDGFRα). Exhibits >30-fold selectivity over a panel of other kinases and exhibits no activity against cytochrome P450. Causes tumor regression of leukemia cell xenografts in mice. Also reduces joint swelling and inflammation in a mouse model of collagen-induced arthritis. Orally active.Specifications
| >99% | |
| AC 710 | |
| 562.7 | |
| AC 710 |
For Research Use Only