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  6. 5-Fluoro-2'-deoxyuridine, 98+%, Thermo Scientific Chemicals

5-Fluoro-2'-deoxyuridine, 98+%, Thermo Scientific Chemicals

Product Code. 11389205
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Quantity:
100 mg
500 mg

Description

5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.

Notes
Store in a cool place.Incompatible with strong oxidizing agents and strong bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 50-91-9
Molecular Formula C9H11FN2O5
Molecular Weight (g/mol) 246.19
MDL Number MFCD00006530
InChI Key ODKNJVUHOIMIIZ-RRKCRQDMSA-N
Synonym floxuridine, 2'-deoxy-5-fluorouridine, 5-fluoro-2'-deoxyuridine, 5-fluorodeoxyuridine, fluorodeoxyuridine, floxuridin, fudr, deoxyfluorouridine, fluoruridine deoxyribose, fdurd
PubChem CID 5790
ChEBI CHEBI:60761
IUPAC Name 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
SMILES OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(F)C(=O)NC1=O

Specifications

Melting Point 148°C to 151°C
Quantity 100 mg
UN Number UN2811
Beilstein 2645818
Merck Index 14,4112
Solubility Information Soluble in water,alcohol,isopropyl alcohol,methanol,aqueous buffers,acetone,dimethyl sulfoxide,and ethanol. Insoluble in ether,benzene and chloroform.
Formula Weight 246.2
Percent Purity ≥98%
Chemical Name or Material 5-Fluoro-2'-deoxyuridine

Safety and Handling

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Product Identifier
  • 5-Fluoro-2'-deoxyuridine
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 3
  • Serious eye damage/eye irritation Category 2
  • Germ cell mutagenicity Category 2
  • Skin corrosion/irritation Category 2
 Hazard Statement
  • H301-Toxic if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H341-Suspected of causing genetic defects.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P202-Do not handle until all safety precautions have been read and understood.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
 Supplemental information
  • MIXTURE LIST-Contains : Floxuridine

RUO – Research Use Only

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