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1,1,1-Trifluoroacetone, 95%, Thermo Scientific Chemicals
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Quantity:
25 g
100 g
Description
1,1,1-Trifluoroacetone is used in a synthesis of 2-trifluoromethyl-7-azaindoles starting with 2,6-dihalopyridines. The derived chiral imine was used to prepare enantiopure α-trifluoromethyl alanines and diamines via a Strecker reaction followed by either nitrile hydrolysis or reduction. And also used as a useful molecule in synthesis reactions.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1,1,1-Trifluoroacetone is used in a synthesis of 2-trifluoromethyl-7-azaindoles starting with 2,6-dihalopyridines. The derived chiral imine was used to prepare enantiopure α-trifluoromethyl alanines and diamines via a Strecker reaction followed by either nitrile hydrolysis or reduction. And also used as a useful molecule in synthesis reactions.
Solubility
Insoluble in water.
Notes
Air Sensitive. Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
1,1,1-Trifluoroacetone is used in a synthesis of 2-trifluoromethyl-7-azaindoles starting with 2,6-dihalopyridines. The derived chiral imine was used to prepare enantiopure α-trifluoromethyl alanines and diamines via a Strecker reaction followed by either nitrile hydrolysis or reduction. And also used as a useful molecule in synthesis reactions.
Solubility
Insoluble in water.
Notes
Air Sensitive. Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Specifications
Specifications
Melting Point | <-78°C |
Density | 1.252 |
Boiling Point | 21°C to 24°C |
Flash Point | −31°C (−24°F) |
Odor | Chloroform-like |
Refractive Index | 1.3 |
Quantity | 25 g |
UN Number | UN1993 |
Beilstein | 1748614 |
Sensitivity | Hygroscopic |
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RUO – Research Use Only
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