CAS RN 552292-08-7

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Rolapitant, MedChemExpress

MedChemExpress Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model.

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Specifications

Molecular Weight (g/mol)	500.48
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Rolapitant
Grade	Research
SMILES	C[C@@](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)([H])OC[C@@]2(C3=CC=CC=C3)CC[C@@](CCC4=O)(N4)CN2
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.65%
CAS	552292-08-7
Solubility Information	DMSO : ≥ 30 mg/mL (59.94 mM)
Synonym	SCH619734
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₅H₂₆F₆N₂O₂
Formula Weight	500.48

CAS RN 552292-08-7

CAS RN 552292-08-7

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